Drug-Resistant Bacteria on the Rise Among Kids

Dr. Latania Logan

Dr. Latania Logan

Infections caused by a specific type of antibiotic-resistant bacteria are on the rise in U.S. children, according to new study published in the Journal of the Pediatric Infectious Diseases Society. While still rare, the bacteria are increasingly found in children of all ages, especially those 1-5 years old, raising concerns about dwindling treatment options.

“Some infections in children that have typically been treated with oral antibiotics in the past may now require hospitalization, treatment with intravenous drugs, or both, as there may not be an oral treatment option available,” said Dr. Latania K. Logan, lead author of the study and an assistant professor of pediatrics and pediatric infectious disease specialist at Rush University Medical Center.

The team of researchers led by Logan analyzed resistance patterns in approximately 370,000 bacterial cultures from pediatric patients collected nationwide between 1999 and 2011.

They found that the prevalence is increasing in a resistant type of bacteria, which produces a key enzyme, extended-spectrum beta-lactamase (ESBL), that thwarts many strong antibiotics, making them ineffective.

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New, Comprehensive, State-of-the-Art Center for Women and Infants to Open at Rush

The New Rush Family Birth Center to Be the City’s Most Advanced Facility for Women’s and Children’s Services

Ivy's Story

Ivy’s Story

The opening of the new Rush Family Birth Center will offer every service related to delivery and caring for a baby on the same floor.

“As part of the Rush Transformation plans that led to our new Tower building, the new Rush Family Birth Center was designed with the mindset of meeting families’ needs and providing patient safety and optimal outcomes,” said Dr. Larry J. Goodman, CEO at Rush.  “We have always provided advanced, quality care that is evidence based.  Now, we have a new facility that matches the type of care we provide mothers and their newborns.”

The new Rush Family Birth Center is located on a single floor at Rush and scheduled to open on March 9.

The space was designed with four key care concepts, which were to provide adjacency, privacy, family space and mother baby bonding. The new center has large, individual rooms to keep moms, babies and families together throughout their journey.

No other hospital in Illinois has located its Neonatal Intensive Care Unit immediately adjacent to labor and delivery to afford newborn infants in distress specialty care in the first minutes of life. Patient safety as well as convenience inspired the design.

“The first 10 minutes of life are critical to newborns who come into the world in distress,” said Dr. Robert Kimura, neonatologist at Rush.  “Because of the way we designed these new facilities, babies that need special care can be put in the hands of neonatal medicine intensive care specialists within seconds after delivery.

“At Rush, the birthing suites and operating rooms are right next to the NICU resuscitation room, so that a team of specialists can immediately and optimally care for babies in crisis,” said Kimura.

The antepartum rooms also are near labor and delivery, so in urgent situations women and their babies can promptly get the care they need.

Keeping services close and right next door to each other limits how far and how often babies need to move, which helps limit their risk of infection and reduces exposure to light and sound to help with the baby’s development.

For more information about the new Rush Family Birth Center, visit Rush Transformation.

 Read the Discover Rush story.

 Read the entire news release.

 

Return to Haiti: Jeff Mjaanes’ Blog

Dr. Jeff Mjaanes, orthopedic specialist at Rush University Medical Center, has returned to Haiti to help with ongoing disaster relief efforts and is blogging about his experience in the field. Mjaanes was part of a team of Rush doctors and nurses who volunteered to help with disaster relief efforts in Haiti in 2010 just after the earthquake hit.

Mjaanes has been having trouble getting Internet service during the day, but he just sent us an update and a few pictures.  

Tuesday, October 16, 2012, at 8 p.m. CT: Went to another marginal community today on outskirts. Saw 200 people. Most of these folks have no access to health care for even basic needs.

Saw a 35 yo man who escaped a collapsing building during the quake. Jumped two floors to ground. Injured left knee – had surgery at the time – opened him and closed him, saying there’s nothing that could be done. Now he has bone on bone arthritis with avascular necrosis and needs a knee replacement. Four kids and a wife depend on him and he can’t work – all he wants is a normal knee and to work to provide for his family.

So many sad stories – but also many positive ones as well. We work with some fantastic Haitians who are dedicated to these communities and are helping us set up networks with local health care providers to provide for long-term help. Many amazing people … they are what makes this crazy world work!

Monday, October 15, 2012, at 7 a.m. CT: First full day in Haiti done. Lots of folks in tent city Jerusalem. Boy who has been beaten by father for poor grades, turns out he has amblyopia and can’t see. Needs glasses. We’ll get him some. It’s hot and humid but VERY rewarding! Tuesday, we’re off to a different community.

Drug Effective in Treating Fragile X Social Withdrawal

Dr. Elizabeth Berry-Kravis

An investigational compound that targets the core symptoms of fragile X syndrome is effective for addressing the social withdrawal and challenging behaviors characteristic of the condition, making it the first such discovery for fragile X syndrome and, potentially, the first for autism spectrum disorder, a study by researchers at Rush University Medical Center and the University of California, Davis MIND Institute has found.

The finding is the result of a clinical trial in adult and pediatric subjects with fragile X syndrome. It suggests, however, that the compound may have treatment implications for at least a portion of the growing population of individuals with autism spectrum disorder, as well as for those with other conditions defined by social deficits. The study is published online today in the journal Science Translational Medicine.

“There are no FDA-approved treatments for fragile X syndrome, and the available options help secondary symptoms but do not effectively address the core impairments in fragile X syndrome,” said Dr. Elizabeth Berry-Kravis, the lead author of the article. “This is the first large-scale study that is based on the molecular understanding of fragile X syndrome and, importantly, suggests that the core symptoms may be amenable to pharmacologic treatment.” Berry-Kravis is professor of pediatrics, neurological sciences and biochemistry at Rush.

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Rush Children’s Hospital Ranked Highly By U.S. News

U.S.News & World Report’s 2012-13 Best Children’s Hospitals rankings have included Rush Children’s Hospital in two of 10 categories, an increase from one last year. Rush Children’s Hospital was ranked No. 35 in gastroenterology and No. 44 in neonatology.

“The rankings are indicative of the excellent care, dedication and expertise that Rush provides to the sickest children across all of Rush Children’s Hospital programs, and we are glad to see two excellent specialties recognized by U.S. News this year,” said Larry Goodman, MD, CEO of Rush University Medical Center.

The rankings feature 50 hospitals in each of 10 pediatric specialties: cancer, cardiology and heart surgery, diabetes and endocrinology, gastroenterology, neonatology, nephrology, neurology and neurosurgery, orthopedics, pulmonology and urology. Only 80 hospitals across the country ranked in one or more specialties.

U.S. News provides quality-related information in addition to rankings, including survival rates, adequacy of nurse staffing and procedure volume. The rankings have put an increasing emphasis on data that directly reflect hospitals’ performance.

See the news release.